Tamás Kálai Selected Research

HO-4038

1/2009

Cardioprotection by HO-4038, a novel verapamil derivative, targeted against ischemia and reperfusion-mediated acute myocardial infarction.

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Tamás Kálai Research Topics

Disease

10	Neoplasms (Cancer) 01/2022 - 05/2010
5	Ovarian Neoplasms (Ovarian Cancer) 01/2022 - 05/2010
5	Alzheimer Disease (Alzheimer's Disease) 08/2018 - 01/2012
4	Ischemia 01/2009 - 10/2005
3	Myocardial Infarction 01/2009 - 10/2005
2	Neuralgia (Stump Neuralgia) 06/2021 - 12/2020
2	Pancreatic Neoplasms (Pancreatic Cancer) 06/2020 - 06/2019
2	Heart Failure 03/2013 - 09/2008
2	Cardiotoxicity 11/2011 - 01/2007
2	Carcinoma (Carcinomatosis) 11/2011 - 09/2010
2	Infarction (Infarctions) 01/2009 - 10/2007
2	Reperfusion Injury 08/2006 - 10/2005
1	Ovarian Epithelial Carcinoma 01/2022
1	Hyperthermia 06/2021
1	Hyperalgesia 06/2021
1	Adenocarcinoma 06/2020
1	Mitochondrial Diseases (Mitochondrial Disease) 06/2020
1	Tics (Tic) 01/2020
1	Colonic Neoplasms (Colon Cancer) 03/2019
1	Amyloid Plaque 01/2017
1	Pulmonary Hypertension 03/2013
1	Pathologic Processes 01/2012
1	Prostatic Neoplasms (Prostate Cancer) 05/2010
1	Hypertrophy 08/2009
1	Fibrosis (Cirrhosis) 08/2009
1	Vascular Remodeling 06/2009
1	Hyperplasia 06/2009
1	Cardiomegaly (Heart Hypertrophy) 09/2008
1	Cardiomyopathies (Cardiomyopathy) 01/2007
1	Myocardial Ischemia (Ischemic Heart Diseases) 08/2006

Drug/Important Bio-Agent (IBA)

8	(3,5- bis((4- fluorophenyl)methylidene)- 1- ((1- hydroxy- 2,2,5,5- tetramethyl- 2,5- dihydro- 1H- pyrrol- 3- yl)methyl)piperidin- 4- one)IBA 06/2019 - 06/2009
5	AntioxidantsIBA 11/2011 - 01/2007
4	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2009
4	Peptides (Polypeptides)IBA 11/2017 - 01/2012
3	nitroxylIBA 06/2020 - 05/2010
3	PiperidonesIBA 03/2019 - 05/2010
3	Amyloid beta-PeptidesIBA 08/2018 - 12/2015
3	Antineoplastic Agents (Antineoplastics)IBA 08/2011 - 05/2010
3	Poly(ADP-ribose) Polymerase InhibitorsIBA 08/2009 - 10/2005
2	L-2663IBA 01/2022 - 06/2020
2	CalciumIBA 06/2021 - 10/2007
2	Analgesics (Analgesic Drugs)IBA 06/2021 - 12/2020
2	Amyloid (Amyloid Fibrils)IBA 01/2017 - 01/2012
2	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2011 - 01/2007
2	alpha,beta-diacryloxypropionic acid (DAPS)IBA 08/2011 - 05/2010
2	pyrrolineIBA 08/2011 - 10/2007
2	Caspase 3 (Caspase-3)IBA 05/2010 - 05/2010
2	Verapamil (Calan)FDA LinkGeneric 01/2009 - 10/2007
2	Isoproterenol (Isoprenaline)FDA LinkGeneric 09/2008 - 10/2005
2	2- ((2- piperidin- 1- ylethyl)thio)quinazolin- 4(3H)- oneIBA 09/2008 - 10/2005
1	PlatinumIBA 01/2022
1	Carboplatin (JM8)FDA LinkGeneric 01/2022
1	Protons (Proton)IBA 06/2021
1	Amine Oxidase (Copper-Containing)IBA 12/2020
1	Warfarin (Coumadin)FDA LinkGeneric 01/2020
1	Cytochrome P-450 CYP3AIBA 01/2020
1	Ticlopidine (Ticlid)FDA LinkGeneric 01/2020
1	EnzymesIBA 01/2020
1	bergamottinIBA 01/2020
1	Cytochrome P-450 CYP2C9IBA 01/2020
1	Cytochrome P-450 CYP2C19IBA 01/2020
1	Ketoconazole (Nizoral)FDA LinkGeneric 01/2020
1	GadoliniumIBA 01/2017
1	Peroxynitrous Acid (Peroxynitrite)IBA 03/2013
1	Free RadicalsIBA 01/2012
1	FluorenesIBA 01/2012
1	Cisplatin (Platino)FDA LinkGeneric 11/2011
1	CurcuminIBA 11/2011
1	Focal Adhesion Protein-Tyrosine KinasesIBA 09/2010
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2010
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 09/2010
1	ErbB Receptors (EGF Receptor)IBA 09/2010
1	Fatty Acid Synthases (Fatty Acid Synthase)IBA 09/2010
1	Messenger RNA (mRNA)IBA 09/2010
1	Sterol Regulatory Element Binding Protein 1IBA 09/2010
1	Mitogen-Activated Protein Kinase 3IBA 09/2010
1	Hydroxylamine (Hydroxylamine Hydrochloride)IBA 05/2010
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 05/2010
1	Superoxides (Superoxide)IBA 05/2010
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 06/2009
1	NF-kappa B (NF-kB)IBA 06/2009
1	Matrix Metalloproteinases (MMPs)IBA 06/2009
1	TensinsIBA 06/2009
1	N-hydroxypiperidineIBA 01/2009
1	HO-4038IBA 01/2009
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 09/2008
1	CollagenIBA 09/2008
1	Enalapril FDA LinkGeneric 09/2008
1	Glycogen Synthase Kinase 3 betaIBA 09/2008
1	1- hydroxy- 2,2,5,5- tetramethyl- 2,5- diydro- 1H- pyrrole- 3- carboxylic acid (2- (3,4- dimethoxyphenyl)- 5- ((2- (3,4- dimethoxyphenyl)ethyl)methylamino)- 2- isopropylpentyl)amideIBA 10/2007
1	Daunorubicin (Cerubidine)FDA LinkGeneric 01/2007
1	AminesIBA 01/2007
1	AnthracyclinesIBA 01/2007
1	Trimetazidine (Vastarel)IBA 08/2006
1	Reactive Oxygen Species (Oxygen Radicals)IBA 08/2006
1	Nuclear Proteins (Protein, Nuclear)IBA 10/2005
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 10/2005

Therapy/Procedure

6	Therapeutics 06/2020 - 05/2010
1	Drug Therapy (Chemotherapy) 11/2011
1	Injections 11/2011